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CAS NO.1134-01-6
Established in July 2013, BLRH Biotech Co.,Ltd is located in new industrial park, Mancheng District, Baoding City, Hebei Province. It covers a total area of more than 46,000 square meters with total investment of CNY 160 million. It has over 150 employees, 30% of them are developers with Bachelor degrees or above. Our company has full set of lab scale, pilot scale and production facilities. The plant ,which is designed according to China New GMP standard, covers an area of 30,000 square meters with perfect quality management system.
Anhydrous sodium acetate is widely used in sewage treatment, printing and dyeing, food additives and other industries.
As a leader in the sodium acetate industry, BLRH insists on using the best raw materials and technologies to produce the highest quality sodium acetate.
1. High quality requirements
2. Science and technology
3. Strict manufacturing process
4. Excellent customer service
5. Famous brands
High Purity Nω-methyl-5-hydroxytryptamine 1134-01-6 GMP Factory Supply
Description
N-Methylserotonin is a tryptamine alkaloid.Chemically, it is a derivative of serotonin in which a methyl group resides at its alkyl amine. It is also called Nω-methylserotonin (Nω-methyl-5-hydroxytryptamine) to distinguish it from tryptamine-derived compounds in which a methyl group is bonded to the nitrogen atom of the indole group.
N-Methylserotonin is found in plants, animals, and fungi.These include the plants, Actaea racemosa (black cohosh) and Zanthoxylum piperitum,the Green and Golden Bell Frog, Litoria aurea,and Amanita mushrooms.The compound binds to several serotonin receptors, including the 5-HT7 and 5-HT1A receptors, with high affinity (IC50 ≤ 2 nM) and selectivity, and displays agonist activity; besides its direct interaction with the serotonin receptors, N-methylserotonin also acts as a selective serotonin reuptake inhibitor.
Properties
Melting Point | 127.78° C (Predicted) |
Boiling Point | ~402.6° C at 760 mmHg (Predicted) |
Appearance&Form | Oil,Liquid |
Storage Temp | Store at -20° C |
Density | ~1.2 g/cm3 (Predicted) |
Refractive Index | n20D 1.66 (Predicted) |
pK values | pKa: 9.97 (Predicted), pKb: 10.63 (Predicted) |
Ki DataBase | Serotonin 1a (5-HT1a) receptor: Ki= 5 nM (rat); Serotonin 1b (5-HT1b) receptor: Ki= 45 nM (rat); Serotonin 2 (5-HT2) receptor: Ki= 180 nM (rat); Serotonin 2c (5-HT2c) receptor: Ki= 280 nM (human) |
Synonyms | N-Methylserotonin;3-[2-(MethylaMino)ethyl]indol-5-ol;Serotonin Impurity 1 (N-Methyl Serotonin);3-(2-methylaminoethyl)-1H-indol-5-ol,N-Methyl Serotonin |
Application
N-Methylserotonin Oxalate Salt, is the N-methylated derivative of serotonin with similar activity. Studies have identified N-Methylserotonin as a potential active constituent that contributes to the serotonergic activity of black cohosh.