Keywords

• 5-HTP factory
• 4350-09-8 GMP Factory
• 4350-09-8

Quick Details

• ProName: 5-HTP factory 4350-09-8 GMP Factory 5-...
• CasNo: 4350-09-8
• Molecular Formula: C11H12N2O3
• Appearance: white powder
• Application: Mainly as the dietary supplement for M...
• DeliveryTime: Delivery within three days of payment
• PackAge: 25kg/drum or customized
• Port: any port ,China
• ProductionCapacity: 500 Metric Ton/Year
• Purity: 99% min
• Storage: Store at room temperature, airtight, a...
• Transportation: Warehouse in USA, Warehoue in Europe, ...
• LimitNum: 1 Kilogram
• Moisture Content: ≤2.0%
• Impurity: NMT 0.2%
• PH: 4.0-6.0
• Optical Rotation: -30°~-35°
• Loss on Drying: NMT0.5%
• Appearance: white powder
• Odor: Characteristic
• Taste: Characteristic
• Particle Size: 100% through 80 mesh
• Heavy Metals: NMT 10ppm

Superiority

5-HTP factory 4350-09-8 GMP Factory 5-Hydroxytryptophan C11H12N2O3

VDK Nutrition Biotech Co., Ltd. is the largest 5-hydroxytryptophan manufacturer in China, with exclusive fermentation technology

Our 5-HTP was produced by the whole fermentation method, the purity is above 99.7%, and the quality is far better than traditional plant extract products, with an annual production capacity of 500 tons.

As an intermediate of health care products, 5-HIP has a good effect on anti-depression, reducing fatigue and improving sleep.The purity of our 5-HTP produced by biological fermentation technology can reach more than 99%, and as the largest source manufacturer in China, we can fulfill your order on time and in quantity.

Properties of 5-hydroxy-L-tryptophan

Melting point: 270 ° C (dec) (lit.)

Specific rotation: -32.5 ° (C =1,H2Oondrybasis)

Boiling point: 361.16 ° C (roughestimate)

Density: 0.902 g/mLat25 ° C (lit.)

Refractive index: N20 /D1.4850(lit.)

Color: white,

Optical Rotation :(OpticalActivity)[α]22/D30°, C = 1InH2O

Water Solubility: Slightlysoluble

Merck: 14484 7

BRN: 88200

CAS Database: 4350-09-8(CaseDatabase Reference)

EPA Chemical Information: L-5-Hydroxytryptophan(4350-09-8)

Flash: 175 ° F

Storage condition: 2-8°C

Solubility: H2O:10mg/mL

Characteristics: solid

PkA: 2.22±0.10(Predicted)

English name: 5-hydroxytryptophan

Product specification: 10%~99% 5-HTP(HPLC external standard method).

Sub-formula: C11H12N2O3

Sub-quantity: 220.23

External view: kind of white to white fine powder

Physical properties: slightly salty taste,5-HTP insoluble in water, melting point 270℃, rotation -30

Established in July 2013, VDK Nutrition Biotech Co.,Ltd was located in new industrial park, Mancheng District, Baoding City, Hebei Province. It covers a total area of more than 46,000 square meters with total investment of CNY 160 million. It has over 150 employees, 30% of them are developers with Bachelor degrees or above. Our company has full set of lab scale, pilot scale and production facilities. The plant ,which is designed according to China New GMP standard, covers an area of 30,000 square meters with perfect quality management system. With an area of 5,000 square meters, R&D center has well-equipped biotechnology-related Enzyme engineering laboratory, Genetic engineering laboratory, Fermentation pilot scale laboratory, Extraction and Synthesis laboratories. Since the establishment of the company, R&D center has finished 3 industrial products and 5 products are under research, meanwhile established cooperative relations with several well-known universities in China. Our company is mainly engaged in research, development, production and marketing of amino acids and its derivatives such as 5-hydroxytryptophan and melatonin. 5-hydroxytryptophan is all exported to overseas market such as Europe and America.  The annual output value of all products has exceeded CNY 100 million. Our company consistently adheres to “innovation development and green development” during production and dedicates to provide high quality products with reasonable price to global customers.

Process Capability :   Exclusive patent for natural fermentation process

After-sale Service :   Pefect after sales service Products are permanently traceable

Details

5-HTP's drawbacks as a drug

The short half-life (<2h) of 5-HTP may inherently limit the therapeutic potential of 5-HTP, as the systemic 5-HTP exposure levels will fluctuate substantially, even with relatively frequent dosing. Such exposure fluctuations are usually associated with increased adverse event burden, resulting from Cmax drug spikes, and decreased clinical efficacy resulting from sub-therapeutic exposure for large parts of the day. It has been proposed that 5-HTP dosage forms achieving prolonged delivery would be more effective, as is general with short-acting active pharmaceutical ingredients. Unexpectedly, 5-HTP was found to be essential for the growth of human parainfluenza virus in cell culture.

Side effects

Potential side effects of 5-HTP include heartburn, stomach pain, nausea, vomiting, diarrhea, drowsiness, sexual problems, vivid dreams or nightmares, and muscle problems.Because 5-HTP has not been thoroughly studied in a clinical setting, possible side effects and interactions with other drugs are not well known. According to the US National Institute of Health TOXNET, 5-HTP has not been associated with serotonin syndrome or any serious adverse events in humans.Across multiple studies, 5-HTP has also been reported to not cause any noticeable hematological or cardiovascular changes. 5-HTP has also been associated with eosinophilia, but later studies have not found any causal connection.